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Pharmacodynamics of Acetylcysteine

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Pharmacodynamics of Acetylcysteine Empty Pharmacodynamics of Acetylcysteine

Post  lookchem Sun Aug 28, 2011 7:11 pm

Acetylcysteine (or N-acetylcysteine or N-acetyl-L-cysteine), with its CAS registry number 616-91-1, has its IUPAC name of (2R)-2-acetamido-3-sulfanylpropanoic acid. This chemical belongs to the classes of Amino Acids, and it is applied as a pharmaceutical drug and nutritional supplement which is used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose.

Acetylcysteine has been shown to reduce the extent of liver injury following acetaminophen overdose. It is most effective when given early, with benefit seen principally in patients treated within 8-10 hours of the overdose. Acetylcysteine likely protects the liver by maintaining or restoring the Glutathione levels, or by acting as an alternate substrate for conjugation with, and thus detoxification of, the reactive metabolite.

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Pharmacodynamics of Acetylcysteine Empty www.lookchem.com

Post  lookchem Mon Aug 29, 2011 8:16 pm

welcom lookchem.com

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