A non-steroidal anti-inflammatory Drug

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A non-steroidal anti-inflammatory Drug Empty A non-steroidal anti-inflammatory Drug

Post  bluesky on Thu May 20, 2010 11:59 pm

Dexibuprofen is a non-steroidal anti-inflammatory drug. It is a medicine which is used in dental pain relief, dysmenorrhoea, muscular pain relief and osteoarthritis. A meta-analysis of five clinical trials compared tolerability and safety data between Dexibuprofen and racemic ibuprofen. Three PMS studies collected data on 7133 outpatients. In the dosage ratio 0.5:1, Dexibuprofen was found to be at least as efficacious as racemic ibuprofen; 75% of the maximum daily dose of dexibuprofen was equally efficacious as 100% of MDD of diclofenac; no influence was found of meals on bioavailability and a significant doseresponse relationship. In conclusion, dexibuprofen (Seractil) has the stature of a modern NSAID, combining the high efficacy of diclofenac with the good tolerability of ibuprofen, and need not hide behind the new generation of COX-2 inhibitors。


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