Preparation of Adenine(CAS:73-24-5)

The IUPAC name of Adenine is 7H-purin-6-amine. With the CAS registry number 73-24-5, it is also named as 1,6-Dihydro-6-iminopurine. The product's categories are Pyrimidine; Pharmaceutical Intermediates; Purines; Plant Growth Regulator; Nucleobases and their Analogs; Biochemistry; Cytokinins; Nucleosides, Nucleotides & Related Reagents; Nutritional Supplements; Nucleic Acids; Nucleic Acid Purification; Vitamin Ingredients, and the other registry numbers are 22051-90-7; 42911-33-1; 42911-34-2; 520-75-2; 66224-65-5. Besides, it is white to almost white crystalline powder, which should be stored in a cool, ventilated, dry place. This chemical is stable, and incompatible with strong oxidizing agents. In addition, its molecular formula is C5H5N5 and molecular weight is 135.13.

Adenine was also called Vitamin B4.It is no longer considered a true vitamin or part of the Vitamin B complex. However, two B vitamins, niacin and riboflavin, bind with adenine to form the essential cofactors nicotinamide adenine dinucleotide and flavin adenine dinucleotide , respectively. Hermann Emil Fischer was one of the early scientists to study Adenine.Some think that, at the origin of life on Earth, the first adenine was formed by the polymerization of five hydrogen cyanide molecules. However, this has been criticized by some chemists.

Preparation of Adenine: this chemical can be derived from the nucleotide inosine monophosphate (IMP) by using atoms from the amino acids glycine, glutamine, and aspartic acid, as well as fused with the enzyme tetrahydrofolate. Additionally, you can use 4,6-Dichloro-5-nitropyrimidine to produce 4,6-Diamino-5-nitropyrimidine by reaction with Ammonia. And then you would obtain this chemical by the cyclization of 4,6-Diamino-5-nitropyrimidine with Formamide, Formic acid and Sodium thiosulfate.